If 160 million people are using something, trust that these people must be finding value in it. (Seriously, I've never played Farmville, but it has to be awesome/addictive for so many people to play it)
"Oh, you tweet stupid status updates about how you're 'going to the bathroom.' Twitter is stupid!"
Ok, no one does that. In fact, Twitter is far more professional than Facebook. And that's what I see Twitter as. A networking tool. Facebook helps you stay in contact with people you already know. Twitter helps you meet people based on like interests you would never have met in the outside world.
I've made new friends on Twitter. I've gotten new clients on Twitter. And yes, I started following celebrities on Twitter, and now, host a podcast with a leading Hollywood writer.
Twitter doesn't suck. You suck. So, shut up and come follow me.